Carboxyethylarginine Synthase Genes Show Complex Cross-Regulation in Streptomyces clavuligerus
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منابع مشابه
Carboxyethylarginine synthase genes show complex cross-regulation in Streptomyces clavuligerus.
Carboxyethylarginine synthase is the first dedicated enzyme of clavam biosynthesis in Streptomyces clavuligerus and is present in two isoforms encoded by two separate genes. When grown on a liquid soy medium, strains with ceaS1 deleted showed only a mild reduction of clavam biosynthesis, while disruption of ceaS2 abolished all clavam biosynthesis. Creation of an in-frame ceaS2 deletion mutant t...
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ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 2012
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.02600-12